
Thermo Fisher Scientific NR4A3 Monoclonal Antibody (OTI1C1), TrueMAB
인간 NR4A3 단백질을 인식하는 단클론 항체로 Western Blot에 최적화됨. TrueMAB 형식의 Mouse IgG1 항체이며, 고순도 친화 크로마토그래피로 정제됨. PBS/BSA/glycerol 버퍼에 보관되며 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 332–626 of human NR4A3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NOR-1 (NR4A3) is a nerve growth factor-like receptor involved in neuronal development, T-cell apoptosis, and cancer progression. It binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is rapidly but transiently induced by various stimuli. Downregulation of NOR-1 and other NGFI-B family members is associated with drug addiction-prone behavior in Lewis rats. Three human isoforms have been documented: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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