Thermo Fisher Scientific CD90 Monoclonal Antibody (T11D7e)
Mouse와 Rat의 CD90(Thy1) 인식 단일클론 항체로, Flow Cytometry 및 Cytotoxicity Assay에 사용 가능. Thy1.1 마우스에 반응하며 T 세포 제거에 유용. 액상 형태, 1 mg/mL 농도, PBS 버퍼에 0.09% sodium azide 포함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1:5 |
| Cytotoxicity Assay (CT) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T11D7e |
| Immunogen | Xenogeneic rat thymocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_929715 |
Product Specific Information
This antibody recognizes mouse and rat CD90, a monomorphic determinant in rat but polymorphic in mice.
Clone T11D7e reacts with Thy1.1 mice (e.g., AKR and FVB strains), but not Thy1.2 mice such as CBA and BALB/c.
It is useful for removal of T lymphocytes from cell populations by complement-mediated cytotoxicity.
Target Information
CD90 (Thy1) antigen is a GPI-linked glycoprotein and a member of the Immunoglobulin superfamily.
It is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells, and fibroblasts.
CD90 may play roles in cell-cell or cell-ligand interactions during synaptogenesis and other neural events.
It serves as a marker for various stem cells and axonal processes of mature neurons.
Structural studies of CD90 contributed to the foundation of the Immunoglobulin superfamily and the first biochemical characterization of a vertebrate GPI anchor.
Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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