Thermo Fisher Scientific CD90 Monoclonal Antibody (T11D7e)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1:5

-

Cytotoxicity Assay (CT)

Assay-dependent

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

T11D7e

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_929715

Product Specific Information

This antibody recognizes mouse and rat CD90, a monomorphic determinant in rat but polymorphic in mice. Clone T11D7e reacts with Thy1.1 mice (i.e. AKR and FVB mice), but not Thy1.2 mice such as CBA and BALB/c. Clone T11D7e is usefull for removal of T lymphocytes from cell populations by complement mediated cytotoxicity.

Target Information

CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer`s cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.