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Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2A1), TrueMAB
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XPF 단백질을 인식하는 단클론 항체로 Western blot, ICC/IF, Flow Cytometry 등에 사용 가능. 사람, 마우스, 랫, 개 시료에 반응하며 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol buffer에 보관되며 연구용으로 적합.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 08:44
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Thermo Fisher Scientific TA503314 XPF Monoclonal Antibody (OTI2A1), TrueMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
600,200원VAT 포함 660,220원
Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2A1), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A1 |
| Immunogen | Full length human recombinant protein of human ERCC4 produced in HEK293 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.93 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The structure-specific ERCC1/XPF endonuclease complex is involved in the repair of two distinct types of DNA lesions:
- Nucleotide excision repair (NER) for UV-induced lesions and bulky chemical adducts
- Recombination repair of genotoxic interstrand cross-links
In NER, dual incisions occur on both sides of the DNA damage. In mammalian cells, XPG cleaves 3′ of the lesion, while the ERCC1/XPF complex makes the 5′ incision. ERCC1/XPF also likely participates in processing partially repaired recombination intermediates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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