Thermo Fisher Scientific CYB5R3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–1 µg/mL

Product Specifications

Product Specific Information

• Predicted to react with bovine, canine, and rat based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 32,000.

Target Information

CYB5R3 (NADH-cytochrome b5 reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3.
It belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occurring isoforms:

1. Isoform 1: Anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrial outer membrane.
2. Isoform 2: Soluble form found in erythrocytes.

CYB5R3 is involved in:

• Fatty acid desaturation and elongation
• Cholesterol biosynthesis
• Drug metabolism
• Methemoglobin reduction in erythrocytes

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.