Thermo Fisher Scientific TRHR1 Polyclonal Antibody
TRHR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunocytochemistry에 사용 가능. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, 항원 친화 크로마토그래피로 정제. 연구용으로만 사용.
- 카탈로그번호
- ATR-005-xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRHR1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CKQKPTEKAANYS, corresponding to amino acid residues 336–349 of rat Thyrotropin-releasing hormone receptor 1, intracellular C-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
- Ships as lyophilized powder at room temperature; store at -20°C upon arrival.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains, belonging to the G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid–calcium–protein kinase C transduction pathway upon TRH binding.
Reports suggest TRH-R functions as a neurotransmitter and neuroregulator, controlling receptor dimerization and hormone-induced trafficking. It is widely expressed in thyrotroph cells of the anterior pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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