Thermo Fisher Scientific ATG16L1 Polyclonal Antibody
ATG16L1 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, Western blot, IHC, ELISA, IP 등 다양한 실험에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공.
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Thermo Fisher Scientific ATG16L1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 560–610 of human Autophagy-related protein 16-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Autophagy-related protein 16L1 is encoded by the ATG16L gene located on human chromosome 2. Also known as WD30 or IBD10 (Inflammatory Bowel Disease 10), this protein forms a complex with ATG12 and ATG5, known as the Atg16L complex (~800 kDa).
This complex facilitates the coupling or lipidation of LC3 to phosphatidylethanolamine (PE), a key step in autophagy. The ATG16L complex, along with other ATGs such as ATG18 and ATG21, prevents premature cleavage of ATG8-PE by the cysteine protease Atg4 until autophagosome completion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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