Thermo Fisher Scientific RhoB Polyclonal Antibody
RhoB 단백질을 인식하는 Thermo Fisher Scientific의 양친양성 폴리클로날 항체입니다. Western blot과 IHC에 적합하며 인간, 생쥐, 랫드에 반응합니다. 합성 펩타이드 면역원으로 제작된 비결합 항체로 연구용으로 사용됩니다.
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Thermo Fisher Scientific RhoB Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10–50 µg/mL |
| Immunohistochemistry (IHC) | 10–50 µg/mL |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to human, rat, and mouse Rho-related GTP-binding protein RhoB (ARH6, ARHB, H6), conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: RhoB.
Target Information
Rho-related GTP-binding protein (RhoB) mediates apoptosis in neoplastically transformed cells after DNA damage.
While not essential for development, it affects cell adhesion and growth factor signaling in transformed cells.
RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.
Also required for stability and nuclear trafficking of AKT1/AKT, which promotes endothelial cell survival during vascular development.
Serves as a tumor suppressor — deletion of RhoB causes tumor formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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