Thermo Fisher Scientific FXR1 Recombinant Rabbit Monoclonal Antibody (6H25L10)
FXR1 단백질을 표적으로 하는 재조합 토끼 단일클론 항체로, Western blot, ICC/IF, IP, RIP에 사용 가능. 인간 및 생쥐에 반응하며, 높은 특이성과 일관된 로트 간 재현성을 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 2.5 µg/mL | |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | |
| Immunoprecipitation (IP) | Assay-dependent | |
| RNA Immunoprecipitation (RIP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6H25L10 |
| Immunogen | Protein corresponding to human FXR1 (aa400–aa600) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2716881 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Sheep.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
FXR1 is an RNA-binding protein that interacts with FMR1 and FXR2. It may regulate intracellular transport and local translation of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, mainly with the 60S ribosomal subunit. FXR1 is essential for embryonic and postnatal muscle development. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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