Thermo Fisher Scientific VANGL1 Polyclonal Antibody
Rabbit polyclonal antibody against human VANGL1 protein. Validated for Western blot (1:5,000–1:20,000). Antigen affinity purified, 1 mg/mL in Tris-glycine buffer with glycerol. Recommended positive controls include 293T, HeLa, and HepG2 cells. For rese...
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Applications
Western Blot (WB)
- Tested dilution: 1:5,000–1:20,000
- Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–266 of Human VANGL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1 M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4 °C short term; for long term, store at −20 °C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2546564 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (91%), Rat (91%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Vang-like 1 (VANGL1) protein is a human homologue of Drosophila Van Gogh/Strabismus. The VANGL1 gene contains at least seven exons and encodes a protein with four transmembrane domains and a C-terminal Ser/Thr-X-Val motif. Expression is significantly upregulated in several cancer cell lines, including gastric (MKN28, MKN74) and pancreatic (BxPC-3, PSN-1, Hs766T) lines. VANGL1 may mediate intestinal trefoil factor (ITF) responses, serve as a diagnostic marker for hepatocellular carcinoma, and be implicated in neural tube defects (NTD). The gene is located on chromosome 1p11–p13.1.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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