Thermo Fisher Scientific CD44v4 Recombinant Rabbit Monoclonal Antibody (CD44v4, 1700R)
CD44v4 도메인을 인식하는 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. IHC(P)에서 1–2 µg/mL로 사용 가능하며, 고순도의 Protein A 정제 형태로 제공됩니다. PBS(pH 7.4) 용액 내 액상 형태이며, 보존제 없음. 연구용으로만 사용됩니다.
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- 960-RBM10-P1ABX
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CD44v4, 1700R |
| Immunogen | Recombinant fragment corresponding to the v4 domain of human CD44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and some epithelial cells of the intestine and breast.
Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration.
It also plays roles in lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in certain carcinomas, potentially related to metastatic behavior.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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