Thermo Fisher Scientific hnRNP A1 Monoclonal Antibody (4B10)
Western blot, IHC, ICC 등 다양한 응용에 적합한 hnRNP A1 단클론 항체로, 인간 및 동물 시료에 반응합니다. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.25–0.5 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B10 |
| Immunogen | Full-length partially purified human hnRNP A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2717249 |
Product Specific Information
Does not react with hnRNP A2 or B.
Target Information
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). They are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport. While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. hnRNP A1 contains two quasi-RRM domains that bind RNA and is one of the most abundant core proteins in hnRNP complexes, localized to the nucleoplasm. It is exported from the nucleus bound to mRNA and rapidly re-imported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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