Thermo Fisher Scientific Adrenomedullin Monoclonal Antibody (HTA 91a/G2)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:10-1:500

-

Immunocytochemistry (ICC/IF)

1:10-1:500

-

Product Specifications

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

HTA 91a/G2

Immunogen

Chemically synthesized full length adrenomedullin.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.0 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2717247

Target Information

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.