Thermo Fisher Scientific GEF-H1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing GEF-H1 (ARHGEF2) for WB and ICC/IF. Validated for human and mouse, predicted cross-reactivity with monkey, bovine, and horse. Supplied as liquid, affinity purified, 0.5 mg/mL, stored at 4°C or -20°C. For research ...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human ARHGEF2 (aa 20–37, 969–986) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633257 |
Product Specific Information
These rabbit polyclonal antibodies are generated by immunizing animals with specific proteins or peptides. The antibodies are affinity purified from rabbit sera and validated for various research applications. They are intended for Research Use Only, non-hazardous, and non-infectious in nature.
This antibody is predicted to react with Monkey, Bovine, and Horse species.
Target Information
GEF-H1 (ARHGEF2) activates Rho GTPases by promoting GDP-GTP exchange. Rho GTPases regulate key cellular processes such as epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer progression. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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