Thermo Fisher Scientific ERK5 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human MAPK7 (ERK5), validated for WB and ICC/IF. Affinity purified, unconjugated liquid form with 0.5 mg/mL concentration. Suitable for research use only, predicted cross-reactivity with Monkey, Cat, and Rat.
- 카탈로그번호
- 720316
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human MAPK7 (aa 107–122, 500–519) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633256 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
This antibody is intended for Research Use Only and is non-hazardous and non-infectious in nature.
Predicted to react with Monkey, Cat, and Rat.
Target Information
MAPK7 (ERK5) serine/threonine kinase is a member of the MAP kinase family involved in cellular processes such as proliferation, differentiation, transcription regulation, and development.
MAPK7 is activated by MAP2K5/MEK5 and participates in downstream receptor signaling. Upon activation, MAPK7 translocates to the nucleus to regulate gene expression by phosphorylating transcription factors.
Gene deletion in mice leads to defective blood vessel and cardiac development, resulting in embryonic lethality.
ERK5 is critical for endothelial function and blood vessel integrity, and is expressed in many adult tissues—abundantly in heart, placenta, lung, kidney, and skeletal muscle—but not detectable in liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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