Thermo Fisher Scientific CD79a Recombinant Mouse Monoclonal Antibody (PDM0-23)
Recombinant Mouse Monoclonal Antibody (PDM0-23)로 인간 CD79a 단백질을 인식합니다. Western blot 및 IHC(P)에서 사용 가능합니다. 고순도 Protein A 정제, 2 mg/mL 농도 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PDM0-23 |
| Immunogen | Recombinant protein within human CD79a aa 33–143/226 (Extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092997 |
Product Specific Information
- Positive control: Human tonsil tissue, human appendix tissue, human lymph nodes tissue, Raji cell lysates
- Predicted band size: 25 kDa
- Subcellular Location: Cell membrane
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with immunoglobulin (Ig) molecules and the Ig-alpha and Ig-beta components essential for B-cell receptor expression and signaling.
CD79a expression begins at the pre-B cell stage and persists until the plasma cell stage, where it becomes intracellular. It is commonly found in precursor B-cell leukemias, B-cell lymphomas, and some myelomas, but not in myeloid or T-cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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