Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI 1D9), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The BAIAP2 gene encodes a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins and serves as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It associates with Rho GTPase effectors involved in stress fiber formation and cytokinesis, and plays a role in lamellipodia and filopodia formation in motile cells, potentially influencing neuronal growth-cone guidance. It also interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.