Thermo Fisher Scientific Human PKN1 (PRK1), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
Do not store kinase diluted.
Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.

Protein Form: Full Length

Target Information

PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. It can also be activated by phospholipids. PDPK1/PDK1 phosphorylates this kinase, mediating insulin signals to the actin cytoskeleton. Proteolytic activation by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.