Thermo Fisher Scientific Human IRAK4, His Tag Recombinant Protein

Thermo Fisher Scientific Human IRAK4, His Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of the 5 µg, 10 µg, and 20 µg sizes are not recommended; use directly from original packaging.
• For larger sizes, aliquoting can reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
• Do not store diluted kinase.
• When properly stored at -80°C, guaranteed for 6 months from date of purchase.

Protein Form: Recombinant, Full Length

Target Information

IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in Toll/IL-1 signaling pathways. Overexpression of IRAK4 activates NF-kappa-B and MAPK pathways and phosphorylates IRAK1. IRAK4-deficient animals are resistant to LPS challenge and show impaired responses to viral and bacterial infections. Members of the IRAK/Pelle family play a central role in IL-1R/TLR-mediated inflammatory responses and innate immunity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.