Thermo Fisher Scientific Integrin alpha V (CD51) Monoclonal Antibody (3H1A5)
인간 CD51(Integrin alpha V)을 인식하는 마우스 단클론 항체로, Western blot, Flow cytometry, ELISA에 적합합니다. 비결합(Unconjugated) 형태이며, 고순도의 Protein G 정제 제품으로 안정적인 신호 검출에 유리합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Integrin alpha V (CD51) Monoclonal Antibody (3H1A5)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H1A5 |
| Immunogen | Purified recombinant fragment of human CD51 (AA: extra 31–189) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090808 |
Target Information
ITAGV encodes the integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, which combine with multiple integrin beta chains to form distinct integrins.
Among the known associating beta chains (β1, β3, β5, β6, and β8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each interacts with extracellular matrix ligands. The αVβ3 integrin, also known as the Vitronectin receptor (VNR), is one of the most studied. In addition to adhesion, integrins facilitate signal transduction. The ITGB3 protein product forms the integrin beta chain β3, which combines with the αIIb chain in platelets. Integrins are key mediators of cell adhesion and surface signaling.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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