Thermo Fisher Scientific Phospho-4EBP1/2/3 (Thr46, Thr32) Recombinant Rabbit Monoclonal Antibody (23GB3850)
Phospho-4EBP1/2/3 (Thr46, Thr32) 인산화 단백질을 검출하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot, ICC/IF, Flow Cytometry에 적합하며, 인간, 마우스, 랫트에 반응합니다. 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol buffer 보존.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3850 |
| Immunogen | A synthetic peptide of human Phospho-eIF4EBP1/2/3 (Thr46+Thr46+Thr32) (39–53AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
4EBP1, 4EBP2, and 4EBP3 belong to the eukaryotic translation initiation factor 4E-binding protein (4EBP) family.
These proteins regulate protein synthesis by controlling the availability of eIF4E.
Although structurally similar, they differ in tissue distribution and expression levels.
They are expressed in various tissues and cell types, involved in processes such as cell growth, proliferation, and survival.
Dysregulation of 4EBP proteins has been linked to several diseases, including cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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