Thermo Fisher Scientific RXRA Recombinant Rabbit Monoclonal Antibody (ARC0468)
RXRA 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, ICC/IF, ELISA, IP, ChIP 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트에 반응하며, 고순도의 Affinity Chromatography 정제 항체입니다. 연구용으로만 사용 가능합니다.
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- MA535265
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
| ChIP assay (ChIP) | 5 µg antibody for 10–15 µg Chromatin |
| ChIP-sequencing (ChIP-Seq) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0468 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human RXR alpha (P19793) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849167 |
Product Specific Information
Immunogen sequence:
MDTKHFLPLD FSTQVNSSLT SPTGRGSMAA PSLHPSLGPG IGSPGQLHSP ISTLSSPING MGPPFSVISS PMGPHSMSVP TTPTLGFSTG SPQLSSPMNP
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, regulates the transition of proliferating precursor cells (e.g., carcinoma and neuronal precursors) into differentiated cells. The Retinoid X Receptors (RXRs) family—comprising RXR alpha, beta, and gamma—preferentially binds 9-cis-RA and modulates gene transcription by forming heterodimers with other RA receptor families. Retinoids may have therapeutic potential in cervical cancer and play critical roles in neuronal development, synaptic plasticity, learning, and memory.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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