Thermo Fisher Scientific SHP2 Recombinant Rabbit Monoclonal Antibody (3Q4U2)
SHP2 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody (Clone 3Q4U2). Western blot, ICC/IF, ELISA 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, 인체, 생쥐, 랫트 반응성. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SHP2 Recombinant Rabbit Monoclonal Antibody (3Q4U2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3Q4U2 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human SHP2 (UniProt ID: Q06124) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849170 |
Product Specific Information
Immunogen sequence:
MTSRRWFHPN ITGVEAENLL LTRGVDGSFL ARPSKSNPGD FTLSVRRNGA VTHIKIQNTG DYYDLYGGEK FATLAELVQY YMEHHGQLKE KNGDVIELKY
Target Information
The SHP2 protein belongs to the protein tyrosine phosphatase (PTP) family, which regulates cellular processes such as growth, differentiation, mitosis, and oncogenic transformation. SHP2 contains tandem Src homology-2 domains that mediate phospho-tyrosine binding and substrate interactions. It is widely expressed across tissues and plays a regulatory role in signaling events related to mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in SHP2 are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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