Thermo Fisher Scientific PAX6 Recombinant Rabbit Monoclonal Antibody (ARC0367)
PAX6 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA 등에 사용 가능. 인간, 생쥐, 랫드 반응성. HEK293 세포에서 발현된 IgG 형 항체로, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0367 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 323–422 of human PAX6 (NP_0002711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849163 |
Product Specific Information
Immunogen sequence:
TNTYSALPPM PSFTMANNLP MQPPVPSQTS SYSCMLPTSP SVNGRSYDTY TPPHMQTHMN SQPMGTSGTT STGLISPGVS VPVQVPGSEP DMSQYWPRLQ
Target Information
This gene encodes paired box gene 6 (PAX6), one of many human homologs of the Drosophila melanogaster gene prd.
In addition to the hallmark paired box domain, the encoded protein also contains a homeobox domain. Both domains bind DNA and function as transcriptional regulators.
PAX6 is expressed in the developing nervous system and eyes. Mutations are associated with ocular disorders such as aniridia and Peter’s anomaly.
Alternatively spliced transcript variants encoding the same or different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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