Thermo Fisher Scientific SPANXB1 Monoclonal Antibody (OTI2D10), TrueMAB
인간 SPANXB1 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. TrueMAB 형식으로 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며 PBS 버퍼와 trehalose 포함. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific SPANXB1 Monoclonal Antibody (OTI2D10), TrueMAB
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D10 |
| Immunogen | Full length human recombinant SPANXB1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Temporally regulated transcription and translation of several testis-specific genes are required for the formation of mature spermatozoa.
SPANXB1 is a member of the SPANX family of cancer/testis-associated genes located on chromosome X.
SPANX proteins are testis-specific and localize to various subcellular compartments.
SPANXB1 maps to chromosome X adjacent to SPANXB2, which appears to be a duplication of the B1 locus.
SPANXB genes contain an additional 18 nucleotides compared to other family members.
Although SPANXB1 has nuclear localization signals, it predominantly localizes to cytoplasmic droplets of ejaculated spermatozoa, serving as a marker for studying sperm structure and spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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