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Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), Super Bright 600, eBioscience
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Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), Super Bright 600, eBioscience

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마우스 Ly-6G(Gr-1)에 특이적으로 결합하는 1A8-Ly6g 단클론 항체로, Super Bright 600 형광염료로 표지되어 있습니다. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 중성구 탐지 및 제거 연구에 활용 가능합니다. 405 nm 레이저로 여기되어 600 nm에서 방출합니다.

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63-9668-8x (2개 옵션)
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 04:15
Thermo Fisher Scientific 63-9668-82 Ly-6G Monoclonal Antibody (1A8-Ly6g), Super Bright 600, eBioscience 100 ug pk판매 단위 pk ·
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685,300원VAT 포함 753,830원
Thermo Fisher Scientific 63-9668-80 Ly-6G Monoclonal Antibody (1A8-Ly6g), Super Bright 600, eBioscience 25 ug pk판매 단위 pk ·
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254,200원VAT 포함 279,620원

Thermo Fisher Scientific · Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), Super Bright 600, eBioscience

Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), Super Bright 600, eBioscience

Applications and Tested Dilution

Application Tested Dilution Publications
Immunohistochemistry (IHC) - View 4 publications
Immunohistochemistry (Paraffin) (IHC (P)) - View 1 publication
Immunocytochemistry (ICC/IF) - View 2 publications
Flow Cytometry (Flow) 0.5 µg/test View 22 publications

Product Specifications

Specification Description
Published Species Mouse
Host / Isotype Rat / IgG2a, kappa
Recommended Isotype Control Rat IgG2a kappa Isotype Control (eBR2a), Super Bright™ 600, eBioscience™
Class Monoclonal
Type Antibody
Clone 1A8-Ly6g
Conjugate Super Bright™ 600
Excitation / Emission Max 414 / 601 nm
Form Liquid
Concentration 0.2 mg/mL
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Wet ice
RRID AB_2762784

Available Formats

  • Alexa Fluor 700
  • APC
  • APC-eFluor 780
  • Biotin
  • Brilliant UV 395, 563, 661, 737
  • Brilliant Violet 421, 480, 650, 786
  • eFluor 450
  • FITC
  • Functional Grade
  • PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
  • PerCP-eFluor 710
  • Super Bright 436, Super Bright 702
  • Request custom conjugation

Product Specific Information

The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G (Gr-1), a 25-kDa GPI protein expressed exclusively by neutrophils. It plays a role in neutrophil infiltration, recruitment, and migration. Ly-6G associates with B2 integrins (CD11a, CD11b) and modulates their expression and function.

Unlike RB6-8C5, this clone binds only Ly-6G on neutrophils and can be used for neutrophil depletion.

Applications Reported: Flow cytometric analysis
Applications Tested: Tested on mouse bone marrow cells at ≤0.5 µg/test (100 µL volume). Cell number: 10⁵–10⁸ cells/test. Optimal titration recommended.

Fluorochrome Information:
Super Bright 600 is a tandem dye excited at 405 nm and emits at 600 nm. Recommended filter: 610/20 bandpass. Use Super Bright Complete Staining Buffer (SB-4401) when combining multiple Super Bright dyes to minimize non-specific interactions.

Light Sensitivity: Protect from light.
Fixation: Samples can be stored up to 3 days at 4°C in the dark using IC Fixation Buffer (00-8222) or 1-step Fix/Lyse Solution (00-5333). Clone-specific performance should be verified empirically.

Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.


Target Information

Ly6G (Lymphocyte antigen 6 complex locus G6D) is part of the myeloid differentiation antigen Gr-1, along with Ly6C.

  • Molecular weight: 21–25 kDa
  • Expressed by myeloid-derived cells in bone marrow
  • Marker for peripheral neutrophils, monocytes, and granulocytes
  • Correlates with granulocyte differentiation and maturation
  • Involved in anti-tumor responses and modulation of local immune activity

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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