Thermo Fisher Scientific KCNJ2 Polyclonal Antibody
KCNJ2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB와 IHC에 사용 가능. Human, Mouse, Rat 반응성. 동결건조 형태이며 보존제 없음. 연구용 전용으로 높은 특이성과 안정성을 제공.
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Thermo Fisher Scientific KCNJ2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the cytoplasmic domain of KCNJ2 (IRK1, Kir2.1) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse and human.
- Specificity: KCNJ2.
Target Information
The KIR2 subunit family includes 2.1, 2.2, 2.3, and 2.4.
Unlike G protein-coupled KIR3 subunits, KIR2.1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity.
KIR2.1 is expressed in the superior and inferior colliculi and the pontine region of the brain, moderating synaptic transmission.
In the placenta, KIR2.1 is expressed throughout gestation in cytotrophoblast cells.
In the kidney, KIR2.1 colocalizes with KIR5.1 in the proximal tubule.
KIR2.1, 2.2, and 2.3 associate with the membrane-associated guanylate kinase synapse-associated protein 97 in the cerebellum and heart.
Phosphorylation of KIR2.2 by protein kinase A inhibits its association with SAP97.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: OSP00166W-100UL_Kir2.1_KCNJ2_Q64273-1_Rabbit.svg)
(이미지: OSP00166W-100UL_Kir2.1_KCNJ2_Q64273-1_Rabbit_PDP.jpeg)
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