Thermo Fisher Scientific HES5 Polyclonal Antibody
HES5 단백질을 검출하기 위한 Rabbit Polyclonal 항체. Western blot에 적합하며 Human, Mouse, Rat 시료에 반응. Antigen affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관. Notch 신호 경로 연구에 유용.
- 카탈로그번호
- PA550676
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human HES family bHLH transcription factor 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636128 |
Product Specific Information
This antibody detects endogenous levels of total HES5 protein.
Target Information
Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a downstream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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