Thermo Fisher Scientific Phospho-iNOS (Tyr151) Polyclonal Antibody
Human iNOS Tyr151 인산화 부위를 인식하는 rabbit polyclonal antibody로, IHC(P)에서 1:50–1:100 희석으로 사용 가능. Affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관. 인간 대장암 조직을 양성 대조군으로 권장.
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Applications
Tested Application and Dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Suggested Positive Control: Human colon carcinoma tissue
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 151 (Q-Y-Y(p)-G-S) derived from Human iNOS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554274 |
Target Information
Inducible Nitric Oxide Synthase (iNOS) is an enzyme responsible for the production of nitric oxide (NO), a gaseous signaling molecule involved in vasorelaxation, neurotransmission, and cytotoxicity. iNOS expression is inducible by lipopolysaccharide and cytokines such as IFN-γ, TNF, IL-1, and IL-2. The enzyme catalyzes the oxidation of L-arginine to L-citrulline and NO. It is found in various cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells. iNOS dysfunction has been linked to diseases such as achalasia and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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