Thermo Fisher Scientific Cytokeratin 1 Polyclonal Antibody
Human KRT1을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 상피세포성 종양의 감별 진단 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KRT1. Recombinant protein control fragment (Product #RP-92385) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2789759 |
Product Specific Information
Immunogen sequence:
MSRQFSSRSG YRSGGGFSSG SAGIINYQRR TTSSSTRRSG GGGGRFSSCG GGGGSFGA
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately 40 kDa and 68 kDa and isoelectric pH between 4.9–7.8.
Individual human cytokeratins are numbered 1 to 20. Various epithelia express cytokeratins that are characteristic of the epithelium type and related to its degree of maturation or differentiation. Cytokeratin subtype expression patterns are increasingly used to distinguish different types of epithelial malignancies.
Cytokeratin antibodies assist in tumor differential diagnosis using immunohistochemistry on tissue sections and are useful in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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