Thermo Fisher Scientific Cardiac Troponin T Polyclonal Antibody
Cardiac Troponin T 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(Paraffin)에 적합. Human 시료 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNNT2. Recombinant protein control fragment (Product # RP-91306). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789756 |
Product Specific Information
Immunogen sequence:
IEEVVEEYEE EEQEEAAVEE EDWREDEDEQ EEAAEEDAEA EAETEETRAE EDEEEEEAKE AEDGPMEESK PKPRSFMPNL V
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles, and regulates muscle contraction in response to intracellular calcium ion concentration. It plays a crucial role in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression is affected by heart failure. Mutations within the Cardiac Troponin T protein are associated with familial hypertrophic cardiomyopathy and dilated cardiomyopathy. Transcripts undergo alternative splicing resulting in multiple tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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