
Thermo Fisher Scientific Phospho-Lamin A/C (Ser22) Recombinant Rabbit Monoclonal Antibody (LaminACS22-CF12), PE
PE 형광 표지된 인산화 Lamin A/C (Ser22) 특이 재조합 토끼 단일클론 항체로, Flow Cytometry에 적합합니다. 인간 및 마우스 반응성, HEK293 발현 시스템, Protein A/G 정제, PBS+BSA 완충액에 보존됩니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | LaminACS22-CF12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser22 of human phospho Lamin A/C |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897116 |
Additional Formats
Target Information
Lamins are intermediate filament proteins that form a structural matrix on the inner surface of the nuclear envelope. They exist in three forms (A, B, and C) and are expressed in various cell types. Lamins A and C are alternatively spliced products of the LMNA gene, which is associated with multiple disorders such as:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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