Thermo Fisher Scientific CD104 Polyclonal Antibody
CD104(Integrin beta 4)에 특이적인 Rabbit Polyclonal Antibody로, WB와 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol)로 보관. 인간 시료에 반응하며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ITGB4. Recombinant protein control fragment (Product #RP-102715). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790482 |
Product Specific Information
Immunogen sequence:
IVDTVLMAPR SAKPALLKLT EKQVEQRAFH DLKVAPGYYT LTADQDARGM VEFQEGVELV DVRVPLFIRP EDDDEKQLLV EAIDVPAGTA TLGRRLVNIT IIKEQAR
Target Information
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities.
Integrins mediate cell-matrix or cell-cell adhesion and transduce signals that regulate gene expression and cell growth.
This gene encodes the integrin beta 4 subunit, a receptor for laminins. This subunit tends to associate with the alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma.
Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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