Thermo Fisher Scientific ERCC1 Monoclonal Antibody (OTI6H7), TrueMAB
ERCC1 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(P)에서 검증됨. 인간 시료 반응성, 비결합형 형태로 제공. DNA 손상 복구 관련 연구에 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ERCC1 Monoclonal Antibody (OTI6H7), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H7 |
| Immunogen | Full length human recombinant protein of human ERCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair.
In conjunction with SLX4, it participates in the first step of interstrand cross-link (ICL) repair and processes DNA structures that can lead to cytokinesis failure if unresolved.
ERCC1 also plays a role in homology-directed repair (HDR) of DNA double-strand breaks, acting together with SLX4. (Uniprot)
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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