Thermo Fisher Scientific OPRD1 Recombinant Rabbit Monoclonal Antibody (ARC1786)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1786

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OPRD1 (P41143) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OPRD1,uniProtId:P41143-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:372,antigenImageFileName:MA5-38179_OPRD1_P41143-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38179_OPRD1_P41143-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.55 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898096

Product Specific Information

Positive Samples: 293T, SKOV3, Mouse brain, Mouse kidney, Rat ovary, Rat brain

Immunogen sequence: MEPAPSAGAE LQPPLFANAS DAYPSACPSA GANASGPPGA RSASSLALAI AITALYSAVC AVGLLGNVLV MFGIVRYTKM KTATNIYIFN LALADALATS

Target Information

OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimers patients and in the putamen in Parkinsons disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.