Thermo Fisher Scientific IFN alpha Recombinant Rabbit Monoclonal Antibody (0X8Q2)
인간 IFN alpha1을 표적으로 하는 재조합 토끼 단클론 항체. Western blot과 ELISA에 적합하며 높은 특이성과 재현성을 제공. Protein A로 정제된 액상 형태로, -20°C에서 안정적으로 보관 가능. 연구용으로만 사용.
- 카탈로그번호
- MA555214
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 0X8Q2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–189 of human Interferon alpha 1 (IFN-alpha1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
CDLPETHSLD NRRTLMLLAQ MSRISPSSCL MDRHDFGFPQ EEFDGNQFQK APAISVLHEL IQQIFNLFTT KDSSAAWDED LLDKFCTELY QQLNDLEACV MQEERVGETP LMNADSILAV KKYFRRITLY LTEKKYSPCA WEVVRAEIMR SLSLSTNLQE RLRRKE
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component results in activation of multiple signaling pathways mainly involved in innate immune response against viral infection.
In humans, the gene for IFN alpha is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including rats, mice, birds, reptiles, and fish.
IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the antiviral innate immune response, and modulates adaptive immunity. Diseases associated with IFN alpha dysfunction include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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