
Thermo Fisher Scientific ITK Recombinant Rabbit Monoclonal Antibody (7K2Z9)
Recombinant rabbit monoclonal antibody (clone 7K2Z9) targeting human ITK protein. Validated for WB and ELISA. Produced in HEK293 cells and purified via Protein A. Supplied in PBS with BSA and glycerol for stability. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:6,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7K2Z9 |
| Immunogen | Recombinant protein of human ITK/EMT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS (pH 7.3) with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
Target Information
ITK is a tyrosine kinase expressed in T-cells that contains both SH2 and SH3 domains. It plays a role in T-cell proliferation and differentiation. The Tec family of non-receptor tyrosine kinases includes Tec, Itk (also known as Emt or Tsk), Btk (Atk, BPK, or Emb), Bmx, Txk (Rlk), and Dsrc28C. All members contain SH3 and SH2 domains, and except for Txk and Dsrc28C, also possess pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. Itk associates with CD28 and becomes activated following CD28 ligation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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