Thermo Fisher Scientific LRRK2 Recombinant Rabbit Monoclonal Antibody (2R2H10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2R2H10

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-340 of human LRRK2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRRK2,uniProtId:Q5S007-1,ncbiNodeId:9606,antigenRange:100-340,antigenLength:2527,antigenImageFileName:MA5-55216_LRRK2_Q5S007-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55216_LRRK2_Q5S007-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: MGPQDVGNDW EVLGVHQLIL KMLTVHNASV NLSVIGLKTL DLLLTSGKIT LLILDEESDI FMLIFDAMHS FPANDEVQKL GCKALHVLFE RVSEEQLTEF VENKDYMILL SALTNFKDEE EIVLHVLHCL HSLAIPCNNV EVLMSGNVRC YNIVVEAMKA FPMSERIQEV SCCLLHRLTL GNFFNILVLN EVHEFVVKAV QQYPENAALQ ISALSCLALL TETIFLNQDL EEKNENQEND D

Target Information

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson`s disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.