Thermo Fisher Scientific MSH5 Polyclonal Antibody
Thermo Fisher Scientific의 MSH5 Polyclonal Antibody는 인간 MSH5 단백질을 인식하는 토끼 IgG 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보존됩니다. DNA 복제 및 재조합 연구용으로 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | — |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MSH5. Recombinant protein control fragment (Product # RP-105237) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662094 |
Product Specific Information
Immunogen sequence:
METCEDGNDLV FFYQVCEGVA KASHASHTAA QAGLPDKLVA RGKEVSDLIR SGKPIKPVKD LLK
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 80%
Target Information
MSH5 is a member of the mutS family of proteins involved in DNA mismatch repair and meiotic recombination processes. It is similar to a Saccharomyces cerevisiae protein that contributes to meiotic segregation fidelity and crossing-over. MSH5 forms heterooligomers with mutS homolog 4 (MSH4).
Alternative splicing results in four transcript variants encoding three different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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