ELK Biotechnology IL-16 rabbit pAb
IL-16 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 쥐, 생쥐 시료에 반응하며, 세포 내 및 분비형 단백질 검출에 적합. -20°C에서 1년 보관 가능.
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제품명
IL-16 rabbit pAb
제품 개요
IL-16 단백질을 인식하는 토끼 폴리클로날 항체로, 다양한 면역학적 분석(WB, IHC, IF, ELISA)에 사용됩니다. 인간, 쥐, 생쥐 시료에 반응하며, 세포 내 및 분비형 형태 모두 검출 가능합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | IL-16 rabbit pAb |
| Alternative Names | IL16; Pro-interleukin-16 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 IHC-p: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL16 (AA range: 1281–1330) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 140 kDa |
| Gene ID (Human) | 3603 |
| Human Swiss-Prot No. | Q14005 |
| Cellular Localization | [Interleukin-16]: Secreted [Isoform 1]: Cytoplasm [Isoform 3]: Cytoplasm, Nucleus |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which yields two functional proteins. The cytokine function is attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Feb 2010)
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