ELK Biotechnology FGF-12 rabbit pAb
FGF-12 rabbit polyclonal antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, IF, ELISA에 사용 가능합니다. 핵 내 위치 단백질 검출에 적합하며 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관됩니다.
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제품명
FGF-12 rabbit pAb
주요 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | FGF12; FGF12B; FHF1; Fibroblast growth factor 12; FGF-12; Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human FGF12 (AA range: 31–80) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 27 kD |
| GeneID (Human) | 2257 |
| Human Swiss-Prot No | P61328 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in various biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
This growth factor lacks the N-terminal signal sequence present in most FGF family members but contains clusters of basic residues that act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulates in the nucleus but is not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
[provided by RefSeq, Jul 2008]
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