ELK Biotechnology CA IV rabbit pAb
Carbonic anhydrase IV 단백질을 인식하는 rabbit polyclonal antibody로, WB 및 ELISA에 적합합니다. 사람, 생쥐, 랫드 시료에 반응하며, 세포막에 존재하는 GPI-anchored 형태의 CA IV 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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CA IV rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CA4; Carbonic anhydrase 4; Carbonate dehydratase IV; Carbonic anhydrase IV; CA-IV |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human CA IV |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 35 kD |
| GeneID (Human) | 762 |
| Human Swiss-Prot No | P22748 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Species Reactivity | Human; Rat; Mouse |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in various biological processes such as respiration, calcification, acid-base balance, bone resorption, and formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
This gene encodes a glycosylphosphatidylinositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary and certain other capillaries and proximal renal tubules. Its exact function is not known; however, it may play a role in inherited renal abnormalities of bicarbonate transport.
(Provided by RefSeq, Jul 2008)
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