ELK Biotechnology HSP77/76 rabbit pAb
HSP77/76 rabbit pAb는 인간, 생쥐, 랫트에 반응하는 폴리클로날 항체입니다. WB와 ELISA에 적합하며, 내부 영역에서 유래한 합성 펩타이드로 면역화되었습니다. 단백질 안정화 및 폴리펩타이드 접힘 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
HSP77/76 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HSPA7; HSP70B; Putative heat shock 70 kDa protein 7; Heat shock 70 kDa protein B; HSPA6; HSP70B; Heat shock 70 kDa protein 6; Heat shock 70 kDa protein B |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human HSP77/76 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| GeneID (Human) | 3310 |
| Human Swiss-Prot No | P48741 |
| Cellular Localization | COP9 signalosome, extracellular exosome, blood microparticle |
| Species Reactivity | Human; Rat; Mouse |
Background
Caution: Could be the product of a pseudogene.
Function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Induction: Only at higher temperatures, and no basal expression.
Similarity: Belongs to the heat shock protein 70 family.
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