
ELK Biotechnology Ihh rabbit pAb
Ihh 단백질을 인식하는 토끼 폴리클로날 항체로, Western Blot 및 ELISA에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 세포막 및 세포외 위치 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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- ES3753-xxxxx (2개 옵션)
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제품명
Ihh rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | IHH; Indian hedgehog protein; IHH; HHG-2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Ihh. AA range: 209-258 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 45 kD |
| Gene ID (Human) | 3549 |
| Human Swiss-Prot No. | Q14623 |
| Cellular Localization | [Indian hedgehog protein N-product]: Cell membrane; Lipid-anchor; Extracellular side. The N-terminal peptide remains associated with the cell surface. [Indian hedgehog protein C-product]: Secreted, extracellular space. The C-terminal peptide diffuses from the cell; Cell membrane. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning, and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015]
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