ELK Biotechnology α-SMA rabbit pAb
α-SMA rabbit pAb는 사람, 생쥐, 랫트 시료에 반응하는 다클론 항체로 세포골격 내 알파-액틴 검출에 사용됩니다. WB, IHC, IF, ELISA에 적합하며 고순도 IgG로 구성되어 있습니다. 세포 구조 및 운동성 연구에 활용됩니다.
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ELK Biotechnology α-SMA rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | α-SMA rabbit pAb |
| Alternative Names | ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the N-terminal region of human α-SMA (AA range: 84–134) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kD |
| Gene ID (Human) | 59 |
| Human Swiss-Prot No | P62736 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved and play a crucial role in cell motility, structure, and integrity. Alpha, beta, and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in regulating cell motility. This actin is an alpha actin found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants encoding the same protein have been identified.
[provided by RefSeq, Nov 2008]
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