ELK Biotechnology Brm rabbit pAb
Brm 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간 Brm 유래 펩타이드로 면역화되었으며, 핵 내 단백질 검출에 사용됩니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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Brm rabbit pAb
제품 개요
ELK Biotechnology의 Brm rabbit pAb는 인간 Brm 단백질을 인식하는 토끼 폴리클로날 항체입니다. SWI/SNF 복합체 구성 단백질 연구 및 전사 조절 관련 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Brm rabbit pAb |
| Alternative Names | SMARCA2; BAF190B; BRM; SNF2A; SNF2L2; Probable global transcription activator SNF2L2; ATP-dependent helicase SMARCA2; BRG1-associated factor 190B; BAF190B; Protein brahma homolog; hBRM; SNF2-alpha; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000, ELISA: 1/20000 (other applications not yet tested) |
| Immunogen | Synthesized peptide derived from human Brm (AA range: 1328–1377) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 181 kDa |
| Gene ID (Human) | 6595 |
| Human Swiss-Prot No. | P51531 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [Provided by RefSeq, Jan 2014]
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