Thermo Fisher Scientific PGC Polyclonal Antibody
Rabbit polyclonal antibody recognizing human PGC. Validated for WB and IHC-P applications. High purity (>95%) and affinity-purified. Supplied as a liquid at 1 mg/mL concentration. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 280–330 of Human PGC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719178 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1–3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids and shows broad specificity, with preference for bonds involving phenylalanine and leucine. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin, especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine, and isoleucine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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