Thermo Fisher Scientific IL-32 Polyclonal Antibody
IL-32 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(Paraffin) 실험에 적합하며, 고순도(>95%)로 정제된 항체. 면역 및 염증 관련 연구용으로 사용 가능. 연구용(RUO) 제품.
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Thermo Fisher Scientific IL-32 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–2450 of Human IL-32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719177 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Interleukin-32 (IL-32) was initially identified as a transcript (NK4) selectively expressed in lymphocytes and NK cells, with expression increased following IL-2 activation. It was later re-isolated from an IL-18-treated lung carcinoma cell line and renamed IL-32.
IL-32 does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms.
Treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-α, IL-8, and MIP-2. It is also induced in human peripheral lymphocytes after mitogen stimulation and in epithelial cells by IFN-γ, suggesting IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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