
Thermo Fisher Scientific RIT1 Polyclonal Antibody
RIT1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
- 판매단위
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Applications
- Western Blot (WB): 1:500–1:3,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RIT1 (Accession Q92963), corresponding to amino acid residues R184–T219 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900482 |
Product Specific Information
Antibody detects endogenous levels of total RIT1.
Target Information
Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated despite lacking a CAAX box or similar C-terminal lipidation motif. They display 64% amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is fully conserved between murine and human proteins. Although similar to Ras, Rit and Rin interact with Ras-binding proteins such as RalGDS, Rlf, and AF-6, but not with Raf kinases, RIN1, or the p110 subunit of PI3 kinase. Thus, Rit and Rin may regulate signaling pathways distinct from those controlled by Ras.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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