Thermo Fisher Scientific HIRIP3 Polyclonal Antibody
Human HIRIP3 단백질에 특이적인 Rabbit Polyclonal Antibody. IHC(P)와 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS 및 40% 글리세롤 버퍼에서 액상 형태로 제공되며, 연구용으로만 사용.
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Thermo Fisher Scientific HIRIP3 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HIRIP3. Recombinant protein control fragment (Product #RP-103496) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642446 |
Product Specific Information
Immunogen sequence:
KEMQEFTRSF FRGRPDLSTL THSIVRRRYL AHSGRSHLEP EEKQALKRLV EEELLKMQVD EAASREDKLD LTKKGKRPPT PCSDPE
Highest antigen sequence identity to the following orthologs:
- Mouse: 67%
- Rat: 27%
Target Information
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins (HIRIPs) have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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