
Thermo Fisher Scientific BMI-1 Polyclonal Antibody, DyLight 550
BMI-1 단백질을 인식하는 DyLight 550 결합 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. Western blot 및 면역세포염색(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to an internal region (within residues 1–100) of the human Bmi1 protein |
| Conjugate | DyLight™ 550 |
| Excitation / Emission Max | 556 / 570 nm |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 50 mM sodium borate |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153732 |
Product Specific Information
Suggested positive control: human and mouse skeletal muscle.
Target Information
Component of the Polycomb group (PcG) multiprotein PRC1 complex, required to maintain transcriptionally repressive states of many genes, including Hox genes, during development.
Acts via chromatin remodeling and histone modification; mediates monoubiquitination of histone H2A (Lys-119), leading to heritable changes in chromatin expressibility.
Within the PRC1 complex, BMI-1 stimulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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